The Secret Clock of Aging: Telomeres, Longevity, and Peak Performance, EP 314

The Betty White Test Vision

SPEAKER_01 0:00

I'm talking about what I call the Betty White test. Okay. I show pictures of Betty White when she was 85 and 25. And I say, anybody here not know which photo was taken first? I want to see people look, feel, and behave. I'm not interested in knowing what my biomarkers and my blood say. I want to look, feel, and behave like I'm 25 again. And I think that is going to happen when we have something potent enough to actually lengthen and win that tug award in all the cells. And that's three years away. If we could just get this research done, I just want to do the research.

SPEAKER_02 0:35

So your vision is that this discovery will reverse wrinkles and gray hair and just completely make us young again.

SPEAKER_01 0:49

Yeah. Collagen and elastin are definitely been shown to be their production is controlled by telomer lengths.

Welcome And Guest Background

SPEAKER_00 0:58

Hello, friends. Welcome to the Champions Mojo podcast, where we bring you interviews and topics to help you live well and swim well, conversations especially meaningful for master swimmers and anyone striving to perform better in the water or in life. We're here to champion you. And now your host, Kelly Pallas.

SPEAKER_02 1:19

Hello, friends. I could not be more excited about today's show, and we are going to learn just how fortunate we are to have a guest like Dr. Bill Andrews. Dr. Andrews, welcome to Champions Mojo, and then I'm going to give your introduction.

SPEAKER_01 1:35

And please call me Bill.

SPEAKER_02 1:36

Oh, Bill. Okay, well, Dr.

SPEAKER_01 1:38

Andrews, no more doctor.

SPEAKER_02 1:40

Okay, okay, Bill. I I appreciate that. Dr. Bill Andrews is a molecular biologist, gerontologist, and the ultimate champion of the telomere theory of aging. As the founder and CEO of Sierra Science, his entire professional mission is on a single purpose, the audacious goal of finding a medical cure for human aging. He views aging not as an inevitable natural law, but as the biological clock governed by the shortening of telomeres, the protective caps on the end of our chromosomes. He is also a passionate ultramarathoner who frequently competes in grueling 100-mile races. And a little known fact, his connection to water, he was the world record holder for barefoot skiing, the speed record at 74.93 miles per hour back in the day. He's also cemented his legacy as a true pioneer when he led the landmark biotech research team that first discovered and cloned human telomeres, the exact enzyme that prevents cellular aging by rebuilding our chromosomal caps, an achievement honored by Science Magazine as a top 10 breakthrough of the year. This groundbreaking discovery earned him National Inventor of the Year, and he has since accumulated over 50 U.S.-issued patents while authoring seminal books like Curing Aging and Telomere Lengthening. Today, as the head of Sierra Sciences, his lab has screened over 300,000 compounds to safely translate this technology into the human body, making him the world's leading voice on the frontier of reversing cellular aging. And I cannot think of an audience that will be more interested in your work than masters, athletes, and athletes that are trying to maintain our youth.

Telomeres Explained With Shoelaces

SPEAKER_02 3:42

So what are telomeres? Where are they and how do you look at them?

SPEAKER_01 3:48

Well, they're found on the very tips of our chromosomes. Our chromosomes are the things inside of all of our cells that give us our hair color, our eye color. Our chromosomes are like long strings of beads called the beads are called bases. And if you think of this long string of beads as a shoelace, and your shoelace has have these caps at the very tips of your shoelaces called aglets, that's what telomeres are to our chromosomes. Telomeres are the aglets of our chromosomes, and they play a role of protecting our chromosomes, similar to the way aglets on our shoelaces protect our shoelaces. Now, the difference is that the only way that the aglet on our shoelaces get shorter is from wear and tear. Whereas wear and tear is only a problem if you are like a severe smoker or have some other really dangerous lifestyle habit, like being a lot of we're on a lot of radiation and stuff like that. So the telomer shortening is not really a wear and tear. It's actually a process called the end replication problem, where every time a cell divides and a new DNA has to be made so that the two daughter cells have the same DNA. When a new DNA is made, the cell lacks the ability to make the new DNA all the way to the very end.

SPEAKER_02 5:14

So what would be the first thing, Bill, that we should be thinking about with extending our telomeres?

SPEAKER_01 5:24

Think of in all those cells of our body, it's a one-sided tug of war. We have telomeres getting shorter and shorter and shorter. But there are things that we can do now that we we can add people to the other side of the tug of war to lengthen them, but not yet to the point where we can win the tug-of-war, except by a protocol called telomerase gene therapy, which is expensive and risky and still in clinical studies. You said that we cloned telomeres. Well, we actually cloned the enzyme called telomerase. Telomerase is the enzyme that lengthens the telomeres, okay, is the best way to think of it. And telomeres, they get shorter as we age. They're found at the very tips of our chromosomes. I I've known since the 1970s that there had to be something in our cells that were like ride tickets at an amusement park. Something that dictated how that our cells can only divide a limited number of times, and that every time a cell divided, it's it changed in such a way that it got a little bit older and increments that were related to every time a cell divided. We knew that, and the only thing that could explain that was something like ride tickets at an amusement park. And in 1993, somebody else told me that there's things called telomeres at the end of our chromosomes, and they shorten just like ride tickets every time a cell divides. So my whole life has been voted ever since then to figuring out ways of re-lengthening the telomeres through reverse aging. But you called it the theory, telomere theory of aging. It's no longer a theory, it's an absolute fact. Nobody considers this telomere theory of aging a theory anymore. It's actually a fact. It's like there could be other things causing aging, but I like to think of all the things that cause aging as multiple sticks of dynamite burning inside of our cells. And the sticodynamite with the shortest fuse in humans is telomere shortening. Unless you smoke a lot or are obese and things like that, then you might have accelerated aging in other ways that makes other sticks of dynamite have shorter fuses. But for the actually healthy person that lives a good life, uh healthy lifestyle, stuff like that, healthy diet, uh, telomere shortening is the is the absolute most critical thing in our the thing that dictates what our the limit on our lifespan is, and also as it counts for all the changes that we see in all of us as we age. There's a synchrony. We we all can look at everybody and know approximately how old they are. Uh and uh because there's a synchrony, even though there's other things that are causing some slight acceleration or slowing down of aging, there's still that synchrony that that is controlled by the telomers. And so the new DNA is always shorter. And as a result, you've lost a ride ticket every time your your cells divide. Um and it's it's I could keep on talking, but the interrupt anytime you want.

How To Slow Telomere Shortening

SPEAKER_02 8:29

I just I so I have a question just before you get before I forget my question. Uh so you're saying, of course, right at this point, we cannot lengthen our telomeres. Can we do something to keep from shortening them or doing shorter rides or using less tickets?

SPEAKER_01 8:48

Yeah, and and yeah, uh let me let me talk about that now, and then I'll get back to. I didn't say we don't can't lengthen them. I say we can't lengthen them enough to win the tuga war. So we can lengthen, but the lengthening doesn't win the tug award with the shortening yet, except with gene therapy. But a lot of things you can do to prevent what I call accelerated telomer shortening, which is accelerated aging. And one of the worst things people can do is smoke. So smoking causes a lot of free radicals, a lot of inflammation, and both those things cause wear and tear of our telomeres. Okay, and so they get shorter. But so solution there is quit smoking. Okay. The uh, but there's a whole lot of things. Um, like uh any well, anything that causes inflammation, anything that causes oxidative stress is going to cause accelerated telomer shortening. And so I think it's to to decrease the rate of telomer shortening, you've got to lead an anti-inflammatory lifestyle. Okay. Uh and you know, let me go to exercise first because a lot of people say that endurance exercise is very inflammatory. And that's true for some people. If you are in okay, like I I'm gonna use running as an example, but I want to make it clear that endurance exercise can be kayaking, bicycling, hiking, anything.

SPEAKER_02 10:12

But swimming.

SPEAKER_01 10:14

Swimming, yeah, swimming, especially if you're doing one of those like Iron Man triathlons, which I would love to do someday. But the um uh if you if you run, I'm gonna use Ryan's example. If you uh run like once every two weeks and then enter a marathon, you'll do okay. Okay, but you'll be on your hands and knees throwing up afterwards, and you'll be stiff as a board from inflammation for two weeks afterwards. Okay, it's because the body gets this message, the brain gets this message saying something is attacking your joints. Send immune cells to those joints to fight whatever it is, and that's what inflammation is it's accumulation of all these cells that that are fighting whoever the invader is, and then when you're running, there is no invader. Uh so it's a false alarm, but you still get the inflammation. So um so, but if if you are a person who does endurance exercise every day, okay, and then when you go out running, you keep it fun, even during races, and then quit. If it quits being fun and save it for another day, you'll find out that you can exercise all the time, never have inflammatory inflammation. You can may I've I've done measurements, taken blood work from runners before, during, and after ultramarathons, and then interviewed them and found out what you know things or supplements are taken and stuff like that, and was able to come up with the conclusion that boy, if you keep it fun and consistent, your body never ever thinks you have some invader and it thinks it's normal. You build what's called immune tolerance to exercise. And uh, so that's that's one of the best things you can do to decrease the rate of accelerated telomer shortening or accelerated aging, uh, because actually lack of exercise accelerates aging. So it's a Goldilocks effect. So you so no exercise causes aging, too much exercise causes accelerated aging. Find the find the place in the middle.

SPEAKER_02 12:27

So in swim training, swimmers generally, we will work hard and be very sore, and you probably get less sleep because you're getting up to swim. Most most good swim practices are early in the morning, and you might swim hard for several weeks where you're sore and you're tired, and you know, you're probably inflamed from what I'm hearing. And then you taper off. It's it's kind of the standard way that and I'm sure runners do it as well, but swimmers do it. And then when you swim the event, you feel great because you've rested a little bit and you're fresh, and even if it might be a longer swim, maybe you know, a mile or even a 5,000 or something in open water. Is that training approach causing inflammation if we're doing proper nutrition and recovery?

SPEAKER_01 13:21

Well, pain is not inflammation, inflammation. Okay, so you you do expect to get pain, uh pain, but the um uh if the inflammation is something that can then migrate to your joints if you don't do the pain all the time. The body can think the pain's normal, so it's not going to be bothered. And then when the all that inflammation gets to your joints, that's what causes the injuries. Okay. So pain doesn't cause injuries. It's the all the inflammation building up there that actually leads to the injuries that occur oftentimes. The number one secret weapon to doing well in any kind of endurance sports is tapering. Okay. Tapering makes all the difference in the world. And even in my endurance races.

SPEAKER_02 14:08

What is your weekly average?

SPEAKER_01 14:11

Oh, um, it changes, but I'd say lately because of the workload I've got, it's probably like 20 miles on the average. But uh on when I'm really training for 100 mile races, I actually have a routine where I run 70 miles per week. 72, actually. It's like five on Monday, eight on Tuesday, 15 on Wednesday, five on Thursday, nothing on Friday, 25 on Saturday, and 15 on Sunday. Anybody wants to do the math can add that up and it comes at 72 miles.

SPEAKER_02 14:42

Yes. And your age is pretty obvious. You're not in your 40s or 50s after all that you've accomplished in

Training Load Tapering And Being 74

SPEAKER_02 14:50

your life. So um, we always talk about how old we are on this podcast because we all swim in age groups and masters. Tell us your age and that this running routine that you've been doing.

SPEAKER_01 15:01

I'm 74. Uh, but I've been running my whole life. I competed in uh cross-country and track in high school and college. I've been started marathons right after that. Uh been doing ultra marathons since the early 1990s. Um but I want to make one point. You said old.

SPEAKER_02 15:21

Yes.

SPEAKER_01 15:22

I I never use that word.

SPEAKER_02 15:23

I unless it tell me, teach, teach me longer lived. Okay. Longer lived.

SPEAKER_01 15:30

Oh, so you are longer lived than a person that's 45. When I talk about aging at medical conferences and stuff like that, I never talk about eliminating the old from society as a as a mechanism to increase species success in our in in a changing environment. I say eliminating the longer-lived, because but do we want to eliminate the longer-lived? We don't, but our species does.

SPEAKER_02 16:00

Oh, our species does. Why?

SPEAKER_01 16:02

There's several theories on why we age, and several of them are religious, okay, saying that we were kicked out of the Garden of Eden and with the great the great flood that was another reason where God reduced our age. There's other religions that talk about how and God created aging for us so that, or the Greek gods will say, because they didn't want us competing with them. Those ones are all easy to explain. Okay.

Why Evolution Favors Aging

SPEAKER_01 16:28

The toughest one to explain is why would evolution have us age? And more importantly, why did we never evolve a way not to age? Okay. Now, I'm a scientist, so I have no beliefs in anything unless I absolutely know for certain. So I'm not going to say one way or another, but the but the evolutionary explanation for why we age is, and it's not a theory, it's a it's a fact right now. There's absolutely no question about it. In order for a species to survive rapidly changing environments, the best thing that species can do is have a lot of diversity within the species, so that the chances increase that at least some members of that species will survive the new environment. Okay, so how does a species increase uh diversity? Well, the biggest thing that ever happened to increase diversity was two billion years ago, was the onset of sexual reproduction, because then we started shuffling our genes, and that created a tremendous amount of diversity. Well, almost just like a few million years after that, we evolved aging because it turned out there was more diversity created by allowing the offspring to interbreed as opposed to the parents rebreeding. Okay, so when you let the offspring, they had already a tremendous amount of diversity because of the uh breeding between the parents, when you let the offsprings interbreed, they had even more diversity in their grand and the parents' grandchildren. So it turned out that almost all successful species from success by surviving rapidly changing environments did so by finding a way to eliminate the longer-lived. Okay, so genetics can cause things to accelerate telomer shortening, too. So so that's why our average age is pretty much in the uh high 70s, early 80s, as opposed to 125. And nobody in modern days has ever lived to be 125. Even the stories of some woman named John Kalmet living to be 122 have now been shown not to be true. Her daughter took her place to prevent inheritance taxes. And and so that maybe there's been one person that says lived to be 120. But but what I'm doing, and in fact, what I'm doing right now, even though we can't win the tug of war, things that I have discovered so far can actually add people to the lengthening side of the tug of war, even though it's not winning, it's slowing it down. And I believe that people are now going to be exceeding 125 years, not just lifespan, but also health span. So to be healthy too. There are 80-year-olds and 90-year-olds that are already using some of my discoveries. Uh, and uh they've they've actually showing reversal of aging. And I this was kind of a surprise, but then I realized no, it shouldn't have been a surprise because we did know already from many publications and work from my labs and other labs that when telomeres get really, really short, they become easier to lengthen. So there's papers published that saying that telomerase, this enzyme telomerase, will preferentially lengthen the shortest telomeres. So when you're 80 or 90 years old and you want to be rejuvenated, you actually can with things that exist now.

SPEAKER_02 20:04

What does

Telovital Stories And Lab Screening

SPEAKER_02 20:05

that look like when you say you are working with or have seen 80 and 90 year olds reverse aging? What does reversing aging look like in those people?

SPEAKER_01 20:16

It's mostly like uh let's say I know one 85-year-old woman who just turned, oh no, I'm sorry, she just turned 95. Okay. That when I first when she starts first started taking one of the products, actually, this is the product right here. It's called Telovital. Okay, it's a company called Touchstone Essentials. I didn't, I didn't make the product, I just believe in the product because it contains several ingredients that I discovered. Okay, and then this company took those ingredients and made this product.

SPEAKER_02 20:46

Do you take it?

SPEAKER_01 20:47

I liked it. That's why it's sitting here. Okay, take it every day. This 90, she was 94 at the time. She was using a walker. She was on Zoom calls with me with her daughter because she sometimes her daughter had to communicate for her. She's very unenthusiastic, very depressed. Now she's dancing at her 95, 95th birthday videos of her dancing at Zoom calls I have with her, she can't shut up. She's the most enthusiastic person on the planet. It's like her hair color is coming back. Her hair's gone from that's not so. As a scientist, I can't say that hair color proves reversalizing because she could be coloring her hair for all I know, but she can't be pretending on the other things I'm seeing. Okay. And also, I gotta say, this is not scientific yet. This is still anecdotal. We have not done clinical studies because I'm focused, I'm not focused on trying to study this product. I'm focused on trying to find ingredients that are even better than the ones in here that will actually win this tug of war. Okay. And so that's what we do here at my company. We have these high. Throughput robots that that can these they don't look humanoid, but they they're robots that can test up to 4,000 different plant extracts or molecules of any kind a day, okay, looking for more and more potent things. The biggest problem with doing these screens is it costs us $2 million a month to do, and we rarely have that kind of funding. So it goes a little bit slower. If we could keep testing 4,000 samples a day, we can extrapolate from all of our successes so far and say that we could win that tug award in three years from now. Okay. And that's uh something that I'm uh really looking forward to. And I think it's gonna change the planet when it happens, because that is, without a doubt, going to make us look, feel, and behave younger again. And I'm not talking about measuring aging by biomarkers. Okay, mostly most of the time when people measure aging by biomarkers, they're not actually measuring, they're measuring something else besides aging. And actually, sometimes the product that they're testing is actually accelerating aging. I'm talking about what I call the Betty White test. Okay, I show pictures of Betty White when she was 85 and 25. And I say, anybody here not know which photo was taken first? I want to see people look, feel, and behave. I'm not interested in knowing what my biomarkers and my blood say. I want to look, feel, and behave like I'm 25 again. And I think that is going to happen when we have something potent enough to actually lengthen and win that tug of war into all the cells. And that's three years away if we could just get this research done. I just want to do the research. People can actually go to my website, which I think you put a link for on there'll be a button there that says key videos and documentaries. And in there they can look at the data that I show from testing everything. Um and I I don't name the product because I I don't want C synthesis letters. And I have gotten my share in the past from actually naming products. But I I call them like brand A, brand B, brand C, brand D for supplements. Uh, and then then there's also I've tested a lot of diets, a lot of lifestyles, and a lot of therapies. And not a single one of them actually lengthens telomeres. Okay. In fact, what they do, and this is I explain this in great depth in some of these videos, they measure the person's telomeres lengths in their blood beforehand, and then measure them again after treatment, and they'll find that after treatment, their telomeres in the blood are longer. And that's true, but they didn't get lengthened, okay? And

When Telomere Tests Mislead You

SPEAKER_01 24:55

they're only measuring the average telomere length. And so I wanna so so I want to use an analogy here. If you have a company and you fire your dumbest employees, the average IQ of your company increases without anybody getting any smarter. Now think of your blood cells as employees, okay? And now think of the treatment as doing something that's killing the cells with the shortest telomers, because there's lots of studies showing that cells with short telomers are more sensitive to toxins and things like that. And hey, you're killing the cells with the shortest telomers. Well, just like your company, the average length of the telomers and the cells that remain are going to be longer. Okay. And this is really scary because people say, well, that's good. The telomers are the average length of telomers are longer, but cells have to divide to replace those killed cells. And as a result, from the cell division, telomers get shorter. So your net result is even though the cells in your blood are longer, your the the whole, those telomers in your whole body are short. Okay, so you're accelerating aging. The other sign of the analogy, imagine that company, now you hired a bunch of geniuses. Again, the average IQ of your company increases without anybody getting any smarter. That same thing can happen if the treatment or supplement or whatever you're doing is actually uh like causing an immune response. Okay. There's cells in your bone marrow that have long telomers, even when you're 90 years old. Okay. Well, if you induce those cells to divide, which is how you induce an immune response, those cells will start dividing, infiltrate your blood, and suddenly there's new cells added to your blood that have longer telomers. Think of your cell blood cells as employees, and you hired a bunch of geniuses, the average length of the telomeres got longer without any lengthening. But because of all the cell division and in bone marrow, and and subsequently afterwards, you're actually getting older. So this is a really big problem, and it scares me because a lot of people are doing a lot of things they think are reversing their aging. They're actually accelerating their aging because looks can be deceiving.

Skin Treatments Hormones And Tradeoffs

SPEAKER_01 27:22

Okay, it's like so microderm abrasion is a really good example. A lot of people, men and women, use do microderm abrasion or laser treatments and things like that of their skin. What it does is it kills the cells on your surface of your skin. And that causes other cells to divide to replace those cells. And that makes you look younger. But that's what I meant by looks are deceiving. They're actually older. Okay. And that's why a lot of the old, longer-lived cell, the longer-lived movie stars would have prune faces or what called skeleton faces, because they have exhausted all the telomeres in their skin cells. So they can no longer replace those killed-off cells from all the damage they've done by what they thought was rejuvenating their skin. They were accelerating the aging of their skin. The same thing happens with taking any kind of hormone that induces uh cell division. Uh, bodybuilding, unfortunately, does too. Uh, that induces cell division, which causes accelerated telomer shorting.

SPEAKER_02 28:28

Wait, wait, wait. I have to so bodybuilding, like strength training, like real heavy lifting heavy weights, or just bodybuilding?

SPEAKER_01 28:36

Strength training doesn't really do it because really the building up of muscles isn't really from cell division. It's from taking nuclei out of other cells and adding a bunch of nuclei, making the cells bigger. But strength training is okay. But bodybuilding actually does induce a lot of cell division. Uh and but and and this this might be, I don't want to mention names, but you we know a lot of famous bodybuilders that when they get to be in their 60s, they look worse than their friends are the same age. And this is why, but okay, I want to make one some one thing clear.

unknown 29:10

Okay.

SPEAKER_01 29:11

What's the point of living a long time if you're not living? Okay, so if microderm abrasion is important to you, do it. If bodybuilding is important to you, do it. If that was, if that's what makes life worth living to you, do it. Because I'll have a I'll have a solution. Okay. As soon as, as soon as we continue this research enough to get those uh pills, I I want it to be a pill because I don't want to, I want everybody to be afforded. I don't want to be responsible for creating something only the wealthy can afford. I want everybody to be able to afford it. Sometimes I talk with my investors how I just want to drop it from airplanes when we have something that is so potent that it lengthens telomeres, and that can be in three years from now. Uh, but that will reverse all the effects of the microterbourin, all the effects of bodybuilding, all the effects of what is called what I didn't mention before is immune stimulation. When you when you stimulate your immune system, or this is the other thing, when you stimulate the production of stem cells, that causes accelerated telomere shorting. People see benefits from doing that. And I'm glad they do, but it they need to realize that it's gonna, they're gonna pay for it later, okay, when they're when they suddenly start running out of telomer.

SPEAKER_02 30:29

Okay, so I want to circle back a a little bit to the telomere lengthening, but before we do, what are your thoughts on peptides?

Peptides Stem Cells Exosomes Skepticism

SPEAKER_02 30:39

This seems to be a huge thing that I hear from a lot of my athletic friends. Oh, I'm on this peptide or that peptide, and it's gonna do this. There's a peptide for everything now.

SPEAKER_01 30:50

Well, every time there's a new like toy in town or boom or something like that, and peptides is the new toy in town. Um, it be and this reason it's a toy in town is because it's easy for any chiropractor or anybody to actually get into the business because there's companies that will provide them with everything they need, and then they market and things like that. Every time there's a business like that, there's a lot of charlatans. It's a it's an opportunity for charlatans to get into the field. And I would say there's a few peptides that really do work, but most of them are completely fraudulent. Okay. And so it's it's really careful, and that's what that's the reason for I have my own podcast called Up One. Okay. It means take things up a notch. So I don't just do analysis of the literature and stuff like that, what's called meta-analysis to find out if peptides are working. Because there's a lot of even in the scientific peer-reviewed literature, there's a lot of papers that have been published that should have never been allowed to be published because people know how to get them, have them fall through the cracks and get leaked, even though they don't, they're not real, but just so they can use them to market a product. So I do what's called critical meta-analysis, peer-reviewed studies, which means I look at the experimental design, I look at the data analysis, I look at the construct validity, the statistical theory, all the kind of stuff in these papers. And I decide which papers are real and which are not real. And in the case of peptides, I found a lot of the studies to be false. Okay. So in meta-analysis, you get two piles of paper. One pile says one thing, another pile says another thing. When you do critical meta-analysis, you only have one pile. So that's what my podcast called Up One is all about. And people can go to that and hear me talk about these different things. I go to conferences, I speak at conferences, there's booths at the expos at the conferences where people are marketing this peptide and stuff like that. And I'll go up to them. I say, hey, do you have any data showing that your product produces telomerase? And they'll say, Yeah. And then they'll show me the data. I say, that's not, that's not telomerase. And I'll leave them stumped, but I'll tell you, that's it's it's that those peptides don't don't work at all. But there's for every peptide that works, there's 20 to 30 that don't work. Okay, and that's something to be really scary about. The same is true for the stem cell field, the exosome field. Exosome. I don't even know what that is. So stem cells, stem cells, yeah. I gotta start with talking about stem cells. Stem cells are something that we've known that if you inject stem cells into your body, they somehow cause things to get repaired, rejuvenate, and things like that. And it's because they're secreting things called cytokines that would are communicating with cells to make cells fix themselves, either sometimes by cell division. Unfortunately, that causes telomer shortening, but but at least that's it, they're fixing things. Well, uh later on, well, for a long time we've known this, but only later on people start realizing it's actually the exosomes, which are little small cells that don't have chromosomes in them or anything like that, that beat off of the stem cells that are actually doing all the communication. Okay. So a guy in Colorado and a guy down in Panama. Those people are the top stem cell people in the world. And I'll think of their names. In fact, oh, you know, I've always been troublesome at trum remembering names and stuff like that. It's not something that's happened as I've gotten longer-lived.

SPEAKER_02 34:24

I I really I love the longer lived and I want to talk about that a little bit. So you don't you try not to use the word old at all? Or like if if I if somebody asks you how old you are, I mean, well, what is the limit of using the word old? Because are, you know, am I 65 years old or am I 65 years lived?

SPEAKER_01 34:49

Or if I ask somebody how old they are, I I do use the word old. Okay. Because it's a how longer how long lived are you? That that sounds awkward.

SPEAKER_02 34:58

Okay. But it makes a point. I like it actually.

SPEAKER_01 35:01

But but I will call a person old if they are just doing the worst thing possible in their lifestyle and things like that. And they are they're they only have themselves to blame for the condition they're in. Okay. And uh, I mean, if it's because of genetics, I would never call them old. But if it's because they they've been just abusing their bodies the whole time, all their life, uh, then I'll say, hey, you've gotten pretty old. But otherwise I say longer lived. Because let me let me just say this. Living is the greatest thing that ever happened to any of us. Okay. And I challenge anybody to come up with something better that's ever happened to any of us besides living. And I love living, and I hate the idea that living can become any less lovable for any of us just because of this dumb thing called aging. And I call it dumb because people can go and listen to the why we age videos, and you'll see that aging is not necessary. It's actually beneficial for the species, but it's terrible for the individual. And I consider us now to be smarter than evolution. And so I'm trying to undo the effects of evolution, and because I think it was dumb for the individual. And I'm I'm trying to make it so that we we can live long and healthy and uh not cause burdens on society, which I hope other people's will resolve because how will the young ever get jobs if the old ever never retire is the example I always use, is gonna the chaos that's gonna occur from uh making people live longer. We're also gonna get overpopulation, which is another problem that's kind of easy to solve. But I I have faith in the fact that humans can adapt to anything just like we did to the World Wide Web. I don't know if you're younger than me. You might remember how tough it was when we first had it thrust down our throats. Worldwide web, we couldn't use it. Now we can't live without it. I mean, it's like, yeah, so we adapted. We'll adapt to living longer too. And 100 years from now, if somebody says we should ban the cure for aging because there are problems, nobody's gonna want to go back to the way things are now. Nobody really knows how bad things are now because nobody except me goes to hospices or assisted living homes or nursing homes and talks to the people that are there in their 80s and 90s that are stuck in there. They're trapped in there. It's like a jail. They're miserable, they're depressed. They understand their families can't take care of them, stuff like that. But yeah, it I know I'm on tangents.

SPEAKER_02 37:35

So no, no, no. I I took care of my dad, uh, you know, not not directly taking care of him, but I lived near him for the last seven years of his life. He died at 95, and he was a retired attorney, mentally sharp, totally there, 100% there, better memory than anybody I know. And he was just trapped in his body. He he couldn't walk, he was bedbound almost the last year of his life. He had balance issues, he was incontinent. Uh, and his life was miserable. It was his last seven years of his life was just miserable. So, your vision is that this discovery, which we hope will be dropped from airplanes, will reverse wrinkles and gray hair and just completely make us young again.

SPEAKER_01 38:26

Yeah, collagen and elastin are definitely been shown to be their production is controlled by telomer length. Okay. We've done experiments here in the petri dishes, human cells. We've shortened telomeres, lengthened them, shortened them, lengthen them, and we found all kinds of different genes, including collagen, go up and down, up and down, up and down in terms of their production, as just totally with nothing changing except the telomer length. It's really important that people understand this. We can lengthen telomeres, okay, with this product, telovital. Okay, this is the only product that actually does induce the production of telomerase. Okay, so it does add people to the side, but they lengthen. But remember, it's a two-step process. First, the cell divides, the telomeres get shortened, and the length of it comes in and lengthens. Okay, shorten, lengthen. Now, in the case of this, it comes in and lengthens, but not as much as the shortening had occurred. So the so it still loses the tug of war, but it is lengthening. So as a result, it is possibly, we won't know for a few years, gonna allow people to live longer than 125 years. But now let me get to your okay.

SPEAKER_02 39:33

Wait, before you go to the question that I ask. So as a master swimmer who's trying to have my peak performance every year, if this supplement, what is it, telovital, if it actually does what it's uh what you hope it's gonna do, how does that translate into my swim times?

SPEAKER_01 39:57

If you have any cells in your body with critically short telomeres, and you almost certainly do, those ones should get telomeres getting longer, okay, which will be a reversal of aging in your cell. But I gotta qualify, we do not have the studies on that with Televito yet, okay, and we never will because by the time we got those studies done, we'd have a product that's even better than Televital. Okay. But we do know from all kinds of other studies with gene therapies and stuff like that, that when the telomeres do get critically short, they do lengthen, okay, even though the longer ones still get shorter. Okay, and lengthening those critical short short telomers might be the reason why we're seeing the age reversal in these 95-year-old woman and the 84-year-old man that I was telling you about. I haven't actually talked about him at all, but um, and a lot of people are seeing this kind of stuff. So you you should see performance benefits. I have seen performance benefits from Televital. Okay. And my endurance got better. Uh, my vision got better. This product is not my coup de grasse. Okay, my coup de grasse is something that's going to be called televital, but it's going to have ingredients in it that are going to be potent enough to actually win the tug of war in all of our cells, on all of our chromosomes, and and show age reversal. That will increase your chances of being able to live healthy to 125.

SPEAKER_02 41:25

Genetics

Anti-Inflammatory Plan And Key Tests

SPEAKER_02 41:26

plays a big role, and if there's so many other things that are factors that so if certainly, you know, I'll put the link and and the information about the the supplements, but is there like lifestyle changes if if someone just says, I want besides supplements, what what other things would you recommend for anti-inflammatory?

SPEAKER_01 41:47

Is exercise, like I said, keep it fun and keep it uh consistent. Um yoga meditation. I speak at I'm a keynote speaker at yoga meditation conferences a lot. I'll show data showing that they have longer telomers than their friends are the same age that don't do yoga and meditation because it decreases psychological stress, okay, and other things in your body that that cause accelerated telomer shortening. Don't smoke, don't be obese. Obesity causes all kinds of accelerated inflammation and oxidative stress. Be optimistic. Having an anti-inflammatory diet is really important. And here's something that's really, really important. Everybody should take what's called the LCAT test, A-L-C-A-T. And they can Google it if you don't put the link. They can Google it, but just say LCAT tests, otherwise, you'll get all kinds of hits for Alcatraz. Okay. Okay. And it tells you all the foods that cause inflammation in you. Okay. I get this test done every single year. The LCAT test is the only one.

SPEAKER_02 42:49

And it's Is that a blood test?

SPEAKER_01 42:51

It's a blood test. They'll actually arrange to have a phlebotomist come to your home or your office, or you can go to your own phlebotomist and have the blood drawn and send it in. Uh, but I as I said, I get it changed done every year and I find what foods I'm sensitive to, and I quit eating those foods. A year later, it's okay to eat those foods again because I've developed immune tolerance as a as by staying away from that food. For biomarkers of aging, the uh company called True Diagnostic is probably the best company. This guy named Ryan Smith has just put together the best algorithm ever for taking all the markers and coming up with a solution, an answer for what is your biological age. Um, and again, I get no compensation from any of this stuff. I'm my my whole life is just based on trying to make the world happier and healthier.

SPEAKER_02 43:40

Um it's clear. This is a passion of your life, and I really hope we see it in in the near future. The last question to close us out here that I always ask every guest is Is there anything that I have not asked you that you would like to share with the audience?

SPEAKER_01 43:59

People can go to my website and click on this key videos and documentaries and hear about everything else. You're not gonna find it anywhere else.

SPEAKER_02 44:07

Well, we will put all of this in the show notes so people can find that. And certainly I'm so grateful for this time today. I've learned so much. This has just been amazing. And thanks for for all your time here and everything you're doing. And stay on the line because I want to talk to you about how I can get you to swim that 2.4 miles in the in your Iron Man.

SPEAKER_01 44:30

I would love to know. Okay, good.

SPEAKER_02 44:32

I have a technique for you that I think will work.

SPEAKER_01 44:35

Okay. Thank you.

SPEAKER_02 44:36

Thank you.

Closing Thanks And Review Request

SPEAKER_00 44:39

Thank you for listening to the Champions Mojo podcast. Would you consider leaving us a five star review on Apple? That's like getting a best time for us. Kelly and our team would be so grateful. See you next week for another boost of mojo.